Thanks to the collaboration with the TEDDY Network, CVBF has published two new lay summaries explaining the key findings of the DEEP-2 paediatric clinical study in a kid-friendly way. One is tailored for children aged 6-12 years old, while the other targets adolescents aged 12-18.

The DEEP-2 study evaluated an oral formulation for treating iron overload in children and teens with hereditary anaemias like thalassemia and sickle cell disease. These conditions often require frequent blood transfusions, which can lead to excess iron build-up if not managed properly.

The lay summaries use colourful visuals and age-appropriate language to explain the study purpose, methods, and findings.

The 6-12 version takes a narrative approach, personifying red blood cells and using analogies to describe how hereditary anaemias necessitate transfusions and iron chelation therapy. The teen version covers similar points but with higher-level scientific explanations.

Both appealing booklets conclude that the new deferiprone syrup worked effectively and was well-tolerated across all paediatric ages for removing excess iron from chronic transfusions.

The lay summaries can be found on the dedicated DEEP Project website. We plan to create similar child-friendly materials for other paediatric studies as well, in the future.