CVBF provides regulatory, site management, and monitoring support for the AMELIE (Anchored Muscle cELls for IncontinencE) project, Ana Dilo as our Clinical Project Manager of the study oversees and coordinates these activities. AMELIE is a collaborative study funded under the European Union’s Horizon 2020 programme that aims to develop new treatments for faecal incontinence using regenerative medicine approaches.
CVBF is working on feasibility assessments at the 6 sites that will be participating in the clinical trial. The next steps will involve regulatory submissions and qualification visits to get the sites ready for the trial.
The AMELIE clinical trial will assess the safety and efficacy of using autologous skeletal muscle derived cells combined with microcarriers devices to improve cell viability and increase the likelihood of muscle regeneration, contributing to improved continence.